Scientific Programme & Presentations

 

Sunday, 10 September, 2006

Time

Title

Speaker

17.30 - 17.45

Welcome Addresses

17.45 - 18.00

"The European Union's Research Policy in mouse functional genomics" (view Pdf)

Christian Desaintes
European Commission, Belgium

18.00 - 18.15

MUGEN: Integrated functional approaches in mouse models to understand the complexity of human immunological disease (view Pdf)

George Kollias
Biomedical Sciences Research Centre ‘Alexander Fleming', Greece

18.15 - 18.30

"Approaches and developments in mouse phenotyping - towards models of human disease"

Steve Brown
MRC Mammalian Genetics Unit, Medical Research Council, UK

18.30 - 18.45

"The European Conditional Mouse Mutagenesis Program (EUCOMM)"

Wolfgang Wurst
Institute of Developmental Genetics, GSF Research Center, Munich/Neuherberg, Germany

18.45 - 19.00

EMMA: The European Mouse Mutant Archive

(view Pdf)

Martin Hrabe De Angelis
Institute of Experimental Genetics, GSF-National Research Centre for Environment and Health, Germany

19.00 - 19.30

Coffee Break

 

19.30 - 20.00

"The impact of new biology on ethics, politics and society"

Constantine Sekeris
Faculty of Medicine - University of Athens

20.00 - 20.30

"The myth of simplistic biological and genetic causality hinders biomedical research" (view Pdf)

Marc H.V. Van Regenmortel
Ecole Supérieure de Biotechnologie de Strasbourg, France

20.30

Buffet Dinner Reception

 

 

Monday, 11, September 2006

Time

Title

Speaker

Chairs

Marcus Manz and Alberto Mantovani

 

8.30 - 9.00

"Pentraxins as a key component of humoral innate immunity" (view Pdf)

Alberto Mantovani
Instituto Clinico Humanitas, Italy

9.00 - 9.30

"Mouse dendritic cell-mediated NK cell activation"

Paola - Ricciardi Castagnoli
University Biccoca, Milano, Italy

9.30 - 10.00

"Th2 lymphoproliferative diseases resulting from mutations in the LAT adaptor" (view Pdf)

Bernard Malissen
CNRS, France

10.00 - 10.30

‘Persistent HIV-infection in mice with a human immune system" (view Pdf)

Marcus Manz I nstitute for Research in Biomedicine , Switzerland

10.30 - 11.00

Coffee Break

 

Chairs

Erwin Wagner and Dimitris Kioussis

 

11.00 - 11.30

"RET, a key signalling pathway for enteric nervous system development and Hirschsprung's disease"

Vassilis Pachnis
MRC- NIMR, UK

11.30 - 12.00

"RET, a key signalling pathway also for enteric lymphoid system development"(view Pdf)

Dimitris Kioussis
MRC
- NIMR, UK

12.00 - 12.30

"Novel Functions of AP-1(FOS/JUN) in Inflammation and Disease" (view Pdf)

Erwin Wagner
Institute of Molecular Pathology, Vienna, Austria

12.30 - 13.00

"Genetic Analysis of Innate Immunity" (view Pdf)

Bruce Beutler
The Scripps Research Institute, USA

13.00 - 14.30

Lunch Break

 

Chair

Maries van den Broek and James Di Santo

 

14.30 - 15.30

Poster Presentations (10min each)

 

 

"Velocimmune: humanization of immunoglobulin LOCI using velocigene technology"

Sean Stevens
Regeneron Pharmaceuticals, Inc., USA

"Immunological deficiencies of Hfe knock-out mice"

Judit Kiss
University of Heidelberg, Germany

"The activating FcgRI and FcgRIII are dispensable for cartilage- and bone destruction in the collagen induced arthritis (CIA)"

J. Sjef Verbeek
Leiden University Medical Center, The Netherlands

"What is the underlying mechanism of the antitumour activity of the TNF"

An Goethals
Ugent, VIB, Belgium

"Epigenetic control of TH1 cell differentiation"

Lars Rogge
Institut Pasteur, France

15.30 - 16.00

"Dendritic cells as key switch between immunity and tolerance" (view Pdf)

Maries van den Broek
EXPIMMZH, University of Zurich, Switzerland

16.00 - 16.30

"Transgenic mice with sporadic immunogenic tumors"

Thomas Blankenstein
Max-Delbruck Center for Molecular Medicine, Germany

16.30 - 17.00

"Roles for the transcription factor Gata-3 in T and NK cell development" (view Pdf)

James Di Santo
Institut Pasteur, France

17.00 - 17.30

Coffee Break

 

Chair

Guenter Haemmerling

17.30 - 18.00

"Control of tumor immunity by the microenviroenment"

Guenter Hammerling
DKFZ, Germany

18.00 - 18.30

"Regulation and therapeutic exploitation of natural Τ cell responses in human cancer"

Phillip Beck h ove
DKFZ, Germany

18.30 - 19.00

"Erbb2 trasgenic mice: a tool to evaluate the potential efficacy of vaccination in the prevention and cure of carcinomas" (view Pdf)

Elena Quaglino
University of Turin, Italy

19.00 - 19.30

"An inducible mouse model of melanoma expressing a defined tumor antigen"

Benoit van den Eynde
Ludwig Institute for
Cancer Research, Belgium

19.30 - 20.00

"Induction of suppressor function in regulatory T cells" (view Pdf)

Alexander Scheffold
Rheuma-Forschungszentrum, Berlin (DRFZ) Germany

20.00

Free evening

 

 

Tuesday 12 September 2006

Time

Title

Speaker

Chairs

John Trowsdale and Rikard Holmdahl

 

8.30 - 9.00

"From Autoimmune Disease to Genes and back- following an Oxidation Path" (view Pdf)

Rikard Holmdahl
University of Lund, Sweden

9.00 - 9.30

"Understanding the role of HLA-DQ genes in celiac disease: Implications for type 1 diabetes" (view Pdf)

Ludvig Sollid
University of Oslo, Norway

9.30 - 10.00

"MHC genes, functions and interactions" (view Pdf)

John Trowsdale
Department of Pathology, University of Cambridge, UK

10.00 - 10.30

"Archaeaexpress technology applied to the NF-κB signalling pathways" (view Pdf)

Glauco Tocchini-Valentini
CNR- IBC, Italy

10.30 - 11.00

Coffee Break

 

Chairs

Max Cooper and Carola Vinuesa

 

11.00 - 11.30

"Predisposing and Effector Genes in Systemic Autoimmune Diseases"

Ari Theofilopoulos
The Scripps Research Institute, USA

11.30 - 12.00

"Follicular Helper T cells in Lupus Pathogenesis" (view Pdf)

Carola Vinuesa
National University of Australia, Australia

12.00 - 12.30

"Models and genetics of Tolerance and Autoimmunity"

Christophe Benoist
Harvard School of Medicine, USA

12.30 - 13.00

"Human VS Mouse Fc Receptor Homologs"

Max Cooper
Howard Hughes Medical Institute, USA

13.00 - 14.30

Lunch Break

 

Chairs

Dimitris Kontoyiannis and Manolis Pasparakis

 

14.30 - 15.30

Poster Presentations (10min each)

 

 

"Knockout and transgenic models to study the physiological role of TNF"

Sergei A. Nedospasov
DRFZ, Germany

"Macrophage-specific LITAF-deficient mice express reduced LPS-induced cytokine profiling: further evidence for LITAF-dependent LPS signalling pathways"

Salomon Amar
Institut de Génétique et de Biologie Moléculaire, France

"Salivary gland epithelial cells (SGEC) express a novel B7.2 (CD86) splice variant with a putative negative T cell regulatory role"

Efstathia K. Kapsogeorgou
Medical School, University of Athens, Greece

"Decreased TLR4 expression in CRH-NULL mice: a reason for their increased susceptibility to colitis?"

Thalia Teli
Center for Biomedical Research of the Academy of Athens, Greece

"Development of haemato-lymphoid progenitors: dissection of foetal lymphopoiesis reveals asynchronous lineage decision of T and B cells"

A.J. Potocnik
MRC National Institute for Medical Research, UK

15.30 - 16.00

"The IKK/NF-kappaB signalling pathway in inflammation and cancer"

Manolis Pasparakis
University of Cologne, Germany

16.00 - 16.30

TBA

Klaus Pfeffer
Department of Medical Microbiology, Germany

16.30 - 17.00

"Elavl/HuR as a pleiotropic post-trascriptional modifier of innate & adaptive responses"

Dimitris Kontoyiannis
Biomedical Sciences Research Centre ‘Alexander Fleming', Greece

17.00 - 17.30

Coffee Break

 

Chair

Werner Mueller

 

17.30 - 18.00

"Mouse Models for Human Infections" (view Pdf)

Werner Mueller
GBF, Germany

18.00 - 18.30

"Macrophage Activation during Helminth Infection"

Judith Allen
University of Edinburgh, UK

18.30 - 19.00

"Understanding the immunology of malaria using mouse model infections" (view Pdf)

Jean Langhorne
NIMR - MRC, UK

19.00 - 19.30

"Immunoregulation of intestinal helminth infection"

Richard K Grencis
University of Manchester, UK

20.30

Gala Dinner

 

 

Wednesday 13 September 2006

Time

Title

Speaker

Chair

Ari Theofilopoulos

 

9.30 - 10.00

"The human model: a genetic dissection of immunity to infection in natural conditions" (view Pdf)

Jean Laurent Casanova
Université Rene Descartes, France

10.00 - 10.30

"The target cell, epithelium, as initiator and perpetuator of autoimmune lesion: Lessons from Sjogren's syndrome" (view Pdf)

Harry Moutsopoulos
University of Athens, Greece

10.30 - 11.00

"Expression profiling of chronic inflammatory disorders" (view Pdf)

Vassilis Aidinis
Biomedical Sciences Research Centre ‘Alexander Fleming', Greece

11.00 - 11.30

"Understanding TNF function in immunological disease and animal models: From bench to clinic and back to the bench"

George Kollias
Biomedical Sciences Research Centre 'Alexander Fleming', Greece

11.30

Close

 

12.30 -

MUGEN's SAB / PGB & members Meeting